When you are developing a multitenant application, all your tenants (customers) want their design or color coding (theme) to match their brand standards. First, you have to come up with a unique design or layout for your web app which can be neutral and can be customizable to any design easily. By reading this requirement, of course, you get Bootstrap in your mind. By using Bootstrap you can easily make your web app design very flexible and responsive. We all know benefits of using Bootstrap. If you don’t then go to Getbootstrap.com and get it.
Bootstrap can be a base for responsive web applications. You need to create custom CSS by overriding existing Bootstrap classes. You can also make your customization of Bootstrap common for all tenants by using the .less provided by Bootstrap instead of directly using .css.